The 10 Best GLP-1 Weight Loss Programs of 2026Compounded Semaglutide & Tirzepatide From $179/mo

Why MEDVi Stood Out

Most GLP-1 telehealth programs make getting started harder than it should be. Some hide the true monthly cost behind separate program and treatment fees. Others route you through a marketplace where you have to vet individual providers yourself. Many drag you through long questionnaires before you can even see pricing. For someone just looking to get started, the choice fatigue alone is enough to kill motivation.

MEDVi was the program on our list that combined the strongest entry pricing ($179 first month), a bundled flat monthly cost that covers evaluation, treatment, and delivery, and a dedicated care team providing 1:1 guidance. That combination is why it earned a 9.8 overall and why we selected it as our Editor's Choice for 2026. It is also the option most commonly chosen by GLP01 readers this year.

The other programs we reviewed are legitimate and may be a good fit for specific needs. Willow is our top alternative with similarly streamlined all-in pricing and a dedicated care team. Sesame Care gives you direct access to a marketplace of independent providers, which can be useful if you already know which clinician you want to work with. ReadyRx and Clinic Secret are reasonable price-driven alternatives for users who value simplicity.

The Real Cost of a GLP-1 Program

Brand-name GLP-1 options can cost $1,000 to $1,600 per month out of pocket, putting them out of reach for most Americans. That is exactly why telehealth platforms offering compounded alternatives have surged in popularity. Compounded GLP-1 programs, produced by registered 503B facilities, typically range from $45 to $299 per month depending on dosage and the provider's bundled services.

When comparing costs, look beyond the headline price. Some programs include the online evaluation, treatment, delivery, and follow-up care in one flat monthly rate, while others charge separately for each. Factor in whether the program requires a membership fee, how many check-ins are included, and whether dosage increases affect your monthly cost. The providers ranked highest in our list offer the best combination of transparent pricing and comprehensive care.

How We Ranked These Programs

Our editorial team evaluated telehealth GLP-1 weight loss providers across six criteria we believe matter most to a first-time customer: onboarding speed (how quickly you can complete eligibility and speak with a care team), pricing clarity (all-in costs vs. separate fees, membership requirements, hidden charges), ease of use (simplicity of the intake flow, app quality, and day-to-day experience), ongoing support (access to a care team, check-in frequency, messaging), overall value (total cost weighed against what is included), and customer feedback (publicly available reviews and reputation indicators).

Each provider was scored on a 10-point scale based on our editorial review. These scores reflect our opinion as reviewers, not clinical judgments, and the weightings are designed to reward programs that minimize friction for a new customer. Programs marked "Partner" have a commercial relationship with this site and we may earn a commission if you sign up through our links. Partner status does not guarantee a higher ranking, but it does affect which programs we write about most. Non-partner programs are included when they meet our quality threshold. We update these rankings as pricing and services change. Individual experiences will vary, and you should consult a qualified healthcare provider before starting any weight management program.